Hunting for Isocurvature Modes in the CMB non-Gaussianities

We investigate new shapes of local primordial non-Gaussianities in the CMB. Allowing for a primordial isocurvature mode along with the main adiabatic one, the angular bispectrum is in general a superposition of six distinct shapes: the usual adiabatic term, a purely isocurvature component and four additional components that arise from correlations between the adiabatic and isocurvature modes. We present a class of early Universe models in which various hierarchies between these six components can be obtained, while satisfying the present upper bound on the isocurvature fraction in the power spectrum. Remarkably, even with this constraint, detectable non-Gaussianity could be produced by isocurvature modes. We finally discuss the prospects of detecting these new shapes with the Planck satellite.Comment: 9 pages, 2 figure

Massive scalar states localized on a de Sitter brane

We consider a brane scenario with a massive scalar field in the five-dimensional bulk. We study the scalar states that are localized on the brane, which is assumed to be de Sitter. These localized scalar modes are massive in general, their effective four-dimensional mass depending on the mass of the five-dimensional scalar field, on the Hubble parameter in the brane and on the coupling between the brane tension and the bulk scalar field. We then introduce a purely four-dimensional approach based on an effective potential for the projection of the scalar field in the brane, and discuss its regime of validity. Finally, we explore the quasi-localized scalar states, which have a non-zero width that quantifies their probability of tunneling from the brane into the bulk.Comment: 14 pages; 5 figure

Cosmology in a brane-universe

This contribution presents the cosmological models with extra dimensions that have been recently elaborated, which assume that ordinary matter is confined on a surface, called brane, embedded in a higher dimensional spacetime.Comment: 12 pages; Invited review talk at the JENAM 2002 workshop on "The cosmology of extra dimensions and varying fundamental constants", Porto, Portugal, September 200

Bulk gravitons from a cosmological brane

We investigate the emission of gravitons by a cosmological brane into an Anti de Sitter five-dimensional bulk spacetime. We focus on the distribution of gravitons in the bulk and the associated production of `dark radiation' in this process. In order to evaluate precisely the amount of dark radiation in the late low-energy regime, corresponding to standard cosmology, we study numerically the emission, propagation and bouncing off the brane of bulk gravitons.Comment: 27 pages, 5 figures, minor corrections. Final versio

Scalar Kaluza-Klein modes in a multiply warped braneworld

The Kaluza-Klein (KK) modes of a massive scalar field on a 3-brane embedded in six dimensional multiply warped spacetime are determined. Due to the presence of warping along both the extra dimensions the KK mass spectrum splits into two closely spaced branches which is a distinct feature of this model compared to the five dimensional Randall-Sundrum model. This new cluster of the KK mode spectrum is expected to have interesting phenomenological implications for the upcoming collider experiments. Such a scenario may also be extended for even larger number of orbifolded extra dimensions.Comment: 10 pages, Revte

Limits on the integration constant of the dark radiation term in Brane Cosmology

We consider the constraints from primordial Helium abundances on the constant of integration of the dark radiation term of the brane-world generalized Friedmann equation derived from the Randall-Sundrum Single brane model. We found that -- using simple, approximate and semianalytical Method -- that the constant of integration is limited to be between -8.9 and 2.2 which limits the possible contribution from dark radiation term to be approximately between -27% to 7% of the background photon energy density.Comment: 8 page

How useful is ultrasound to evaluate patients with postmenopausal bleeding?

Using a threshold of ≤5 mm, transvaginal ultrasound (TVUS) can be used to identify those patients with postmenopausal bleeding who are at low risk for endometrial cancer, polyps, or atypical hyperplasia at a sensitivity comparable with that of endometrial biopsy and dilatation and curettage (D&C) (strength of recommendation: B, based on systematic reviews of consistent exploratory cohort studies.

An Improved Wideband CMOS Current Driver for Bioimpedance Applications

A wideband, CMOS current driver for bioimpedance measurement applications has been designed employing nonlinear feedback. With the introduction of phase compensation, the circuit is able to operate at frequencies higher than the pole frequency of the output transconductor with minimum phase delay. Moreover, it isolates the poles required for stability from the high frequency characteristics of the output transconductor. The circuit has been simulated in a 0.35-μm CMOS technology and operates from ±2.5 V power supplies. Simulations show that for a 1 mAp-p output current, the phase delay is less than 1° for frequencies up to 3 MHz, rising to 1.5° at 5 MHz. Dual frequency currents to the load are demonstrated

Can transvaginal ultrasound detect endometrial disease among asymptomatic postmenopausal patients?

Transvaginal ultrasound should not replace endometrial biopsy for detection of endometrial disease among asymptomatic postmenopausal patients. Endometrial biopsy has been considered a standard for the clinical diagnosis of endometrial disease among asymptomatic patients, but it is invasive, may be uncomfortable, and may not be able to be performed for some patients with cervical stenosis. Ultrasound evaluation is less invasive and more comfortable and can be performed for patients with cervical stenosis. The positive predictive value of ultrasound is not adequate to allow it to replace endometrial biopsy for screening of asymptomatic women (strength of recommendation: B, based on cohort studies)

Dynamical Evolution of the Extra Dimension in Brane Cosmology

The evolution of the extra dimension is investigated in the context of brane world cosmology. New cosmological solutions are found. In particular, solutions in the form of waves travelling along the extra dimension are identified.Comment: Latex file, 10 page